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The compound has been characterized in rat and mouse cognitive-research models principally scopolamine-induced cognitive impairment, aged-rat cognitive decline, and the APP/PS1 transgenic Alzheimers disease model with reported effects on hippocampal synaptogenesis, dendritic spine density, and Morris water maze performance

S., Huang, S.-Y., Tzeng, N.-S., Chen, K

DRD3, but Not COMT or DRD2, Genotype Affects Executive Functions in Healthy and First-Episode Psychosis Adolescents. American Journal of Medical Genetics